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Is There More Than Meets the Eye?

How Electroretinogram Analysis adds a new Dimension to Retinal Diagnostics

Andreas Maier
10 min readFeb 5, 2025
Is the Electroretinogram the Future of Ophthalmology? Image created by DALL-E.

Electroretinography (ERG) has been a cornerstone in ophthalmology and vision research for decades, enabling us to record the retina’s electrical activity in response to flashes of light. But the real question is: how can we uncover hidden clues in these complex waveforms to diagnose retinal diseases more accurately and earlier than ever before? A remarkable team of scientists from Russia, Korea, Germany, and Australia believes the answer may lie in a powerful collaboration between cutting-edge signal-processing tools and advanced machine learning. In their new study, they have shown that we can greatly enhance the diagnostic utility of ERG signals with a technique called the Short-Time Fourier Transform (STFT) combined with state-of-the-art deep learning architectures. Let us explore the details behind this interesting approach, why it is so timely, and how it could impact the future of retinal health care.

An electroretinogram (ERG) test performed in 2014. Source: Wikipedia, License: CC BY 4.0 SA

Why Is Electroretinography Suddenly at the Center of Attention?

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Andreas Maier
Andreas Maier

Written by Andreas Maier

I do research in Machine Learning and head a Research Lab at Erlangen University, Germany.

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